Infectious Diseases: Archives

CLINICAL PRACTICE GUIDELINE WATCH

Hepatitis B Guidelines, Updated

• September 30, 2009
• Rajesh T. Gandhi, MD

This revised document provides useful information about the prevention, diagnosis, and management of HBV infection.

• Reviewing:
• Lok ASF and McMahon BJ., Hepatology 2009 Sep; 50:661

SUMMARY AND COMMENT

Kawasaki Disease Outside the Usual Age Range

• September 23, 2009
• Robert S. Baltimore, MD

KD in children younger than 1 year or older than 9 years was associated with an increase in coronary artery abnormalities.

• Reviewing:
• Manlhiot C et al., Pediatrics 2009 Sep; 124:e410

SUMMARY AND COMMENT

Histoplasmosis Uncommon After Solid-Organ Transplantation

• September 23, 2009
• Neil M. Ampel, MD

From 1997 through 2007, only 29 cases of proven or possible histoplasmosis were identified among 3436 solid-organ transplant recipients in an endemic area.

• Reviewing:
• Cuellar-Rodriguez J et al., Clin Infect Dis 2009 Sep 1; 49:710

SUMMARY AND COMMENT

Candida Pneumonia in Critically Ill Patients?

• September 23, 2009
• Thomas Glück, MD

Among ICU patients who died with evidence of pneumonia, autopsy revealed no cases of Candida pneumonia, even in those with positive Candida cultures before death.

• Reviewing:
• Meersseman W et al., Intensive Care Med 2009 Sep; 35:1526 Ricard J-D and Roux D., Intensive Care Med 2009 Sep; 35:1500

SUMMARY AND COMMENT

Comparative Efficacy of Seasonal Influenza VaccinesFree

• September 23, 2009
• Lynn L. Estes, PharmD

Inactivated vaccine was more efficacious than live-attenuated vaccine in healthy adults.

• Reviewing:
• Monto AS et al., N Engl J Med 2009 Sep 24; 361:1260

SUMMARY AND COMMENT

2009 H1N1 Influenza — The Pandemic Continues

• September 23, 2009
• Stephen G. Baum, MD

Since the emergence of this virus in spring 2009, the number of infections has remained uncharacteristically high, presaging a bad winter for influenza.

• Reviewing:
• Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2009 Sep 18; 58:1009

SUMMARY AND COMMENT

Klebsiella Bloodstream Infections

• September 23, 2009
• Neil M. Ampel, MD

In the Calgary area, the annual incidence for 2000–2007 was 7.1 per 100,000; older age and underlying diseases increased the risk for death.

• Reviewing:
• Meatherall BL et al., Am J Med 2009 Sep; 122:866

SUMMARY AND COMMENT

New Hope for HIV Vaccine Development

• September 16, 2009
• Rajesh T. Gandhi, MD

Using a novel technique, researchers identified antibodies that neutralize a broad array of HIV strains.

• Reviewing:
• Walker LM et al., Science 2009 Sep 3

SUMMARY AND COMMENT

Which Pneumococcal Vaccine for Adults with COPD?

• September 16, 2009
• Neil M. Ampel, MD

In a small study, serologic responses were generally better with the 7-valent protein-conjugate vaccine than with the currently approved 23-valent polysaccharide vaccine.

• Reviewing:
• Dransfield MT et al., Am J Respir Crit Care Med 2009 Sep 15; 180:499

SUMMARY AND COMMENT

2009 H1N1 Vaccine: Will One Dose Be Enough?Free

• September 16, 2009
• Daniel J. Diekema, MD, MS

A single 15-µg dose of 2009 H1N1 vaccine, without an adjuvant, produced strong immune responses in 97% of healthy adults.

• Reviewing:
• Greenberg ME et al., N Engl J Med 2009 Sep 10 Neuzil KM., N Engl J Med 2009 Sep 10