Inhaled Liposomal Amphotericin B for Prevention of IPA
Summary and Comment Subscription required
Among patients with prolonged neutropenia, liposomal amphotericin B performed significantly better than placebo in preventing invasive pulmonary aspergillosis.
By Neil M. Ampel, MD
May 14, 2008
Covering:
Rijnders BJ et al., Clin Infect Dis 2008 May 1; 46:1401
Aerial Spraying of Insecticide Disrupts WNV Transmission
Summary and Comment Subscription required
The odds of West Nile virus infection were about six times higher in an untreated area than in two treated ones in the same county.
By Mary E. Wilson, MD
May 14, 2008
Covering:
Carney RM et al., Emerg Infect Dis 2008 May; 14:747
M. bovis TB Increasing Among Hispanics in the U.S.
Summary and Comment Subscription required
From 1994 through 2005, Mycobacterium bovis accounted for 45% of pediatric TB cases and 8% of all TB cases in San Diego County, California.
Entecavir Inhibits HIV at Reduced Viral Inoculum
Summary and Comment Subscription required
The HBV drug entecavir has anti-HIV activity at a low viral inoculum and shouldn’t be used in HIV/HBV-coinfected patients who are not receiving combination ART.
By Lynn L. Estes, PharmD
May 14, 2008
Covering:
Lin P-F et al., Antimicrob Agents Chemother 2008 May; 52:1759
First-Line Therapy for HIV-Infected Patients
Virologic suppression is more likely with an efavirenz-based regimen than with a lopinavir/ritonavir-based one.
By Rajesh T. Gandhi, MD
May 14, 2008
Covering:
Riddler SA et al., N Engl J Med 2008 May 15; 358:2095
Hirschel B and Calmy A., N Engl J Med 2008 May 15; 358:2170
Carbapenem-Resistant Enterobacter Infections
Summary and Comment Subscription required
Patients with imipenem-resistant Enterobacter infections were more likely than those with imipenem-susceptible Enterobacter infections to have multiple invasive devices and to die in-hospital.
By Lynn L. Estes, PharmD
May 7, 2008
Covering:
Marchaim D et al., Antimicrob Agents Chemother 2008 Apr; 52:1413
Evaluation of New Fever in Critically Ill Adults: Updated Guidelines
Clinical Practice Guideline Watch Subscription required
This document updates recommendations published in 1998 by the Society of Critical Care Medicine and the Infectious Diseases Society of America.
By Thomas Glück, MD
May 7, 2008
Covering:
O’Grady NP et al., Crit Care Med 2008 Apr; 36:1330
Group B Strep in the U.S.
Between 1999 and 2005, incidence of invasive group B streptococcal disease decreased in neonates but increased in adults.
Overuse of Empirical Antibiotics for Acute Diarrhea
Summary and Comment Subscription required
Examination of Medicaid data from Tennessee revealed that antimicrobials were prescribed for more than 10% of diarrhea episodes, usually without a stool culture.
Trends in MRSA Carriage in the U.S.
Summary and Comment Subscription required
The prevalence of nasal colonization is increasing.
