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Antibiotic Resistance
Physician-authored summaries on the latest research on antibiotic resistance, editorials on antibiotic resistance, and perspectives on antibiotic resistance - drawn from the top medical journals.
You searched for: antibiotic resistance Items 1 to 20 of 94 results
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TB Antibiotic Resistance and Growth Fitness
- July 26, 2006
- Bradley E. Britigan, MD
Mutations that confer antibiotic resistance in Mycobacterium tuberculosis without decreasing bacterial growth fitness may be selected for during human infection.- Covering:
- Gagneux S et al., Science 2006 Jun 30; 312:1944-6.
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Cycling vs. Mixing Antibiotic Therapy in the ICU
- March 10, 2006
- Thomas Glück, MD
In a comparison of two strategies to avoid increased antibiotic resistance in the ICU, neither was clearly a winner.- Covering:
- Martínez JA et al., Crit Care Med 2006 Feb; 34:329-36.
- Bonten MJM and Weinstein RA., Crit Care Med 2006 Feb; 34:549-51.
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Integrons Are Spread by Cross-Transmission
- August 5, 2005
- Neil M. Ampel, MD
Integrons are mobile DNA elements that can capture and carry genes, including those that encode for antibiotic resistance. To ascertain the role of integrons in . . .- Covering:
- Nijssen S et al., Clin Infect Dis 2005 Jul 1; 41:1-9.
- Norrby SR., Clin Infect Dis 2005 Jul 1; 41:10-1.
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Gram-Positive Bacteria and Antibiotic Resistance in Commercial Poultry
- May 24, 2004
- Richard T. Ellison III, MD
A connection between antibiotic use in livestock and the emergence of antibiotic-resistant bacteria is well established. Seeking a better understanding of antibiotic resistance, researchers at . . .- Covering:
- Nandi S et al., Proc Natl Acad Sci U S A 2004 May 4; 101:7118-22.
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Gram-Negative Antibiotic Resistance: News from the Front
- November 1, 1999
- B Britigan
Successful treatment of gram-negative bacteremia is being challenged by increasing antibiotic resistance, the extent of which varies by region. Ongoing monitoring of these trends in . . .- Covering:
- Diekema DJ et al., Clin Infect Dis 1999 Sep ; 29:595-607.
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Bacterial Antibiotic Resistance May Be Very Durable
- June 1, 1998
- R Ellison
Most of us hope that bacteria that acquire antibiotic resistance will thereby incur a survival cost rendering them less hardy and therefore less likely to . . .- Covering:
- Björkman J et al., Proc Natl Acad Sci U S A 1998 Mar ; 95:3949-3953.
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Pneumococcal Resistance in the Post–Conjugate Vaccine Era
- January 24, 2007
- Daniel J. Diekema, MD, MS
Vaccine serotypes are being replaced by penicillin-resistant nonvaccine serotypes.- Covering:
- Hanage WP et al., J Infect Dis 2007 Feb 1; 195:347-52.
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When to Prescribe a New Antibiotic
- July 26, 2006
- Richard T. Ellison III, MD
Mathematical modeling has identified particular situations in which early use of a new antibiotic could be beneficial.- Covering:
- Wang YC and Lipsitch M., Proc Natl Acad Sci U S A 2006 Jun 20; 103:9655-60.
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Hospital-Wide Antibiograms: Good Enough?
- July 12, 2006
- Daniel J. Diekema, MD, MS
Hospital-wide reports can mask between-unit differences large enough to affect empirical antibiotic choice.- Covering:
- Binkley S et al., Infect Control Hosp Epidemiol 2006 Jul; 27:682-7.
- Clinical and Laboratory Standards Institute., 2005;.
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Dirty Tales of Antibiotic Resistance
- February 24, 2006
- Bradley E. Britigan, MD
Multidrug resistance is common among antibiotic-producing soil actinomycetes, and these organisms are a possible reservoir for resistance in human pathogens.- Covering:
- D’Costa VM et al., Science 2006 Jan 20; 311:374-7.
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Antibiotic Cycling May Not Reduce Resistance
- March 28, 2005
- Neil M. Ampel, MD
The increase in organisms resistant to multiple antibiotics is a growing problem worldwide. One strategy to limit resistance in hospitals is antibiotic cycling -- using . . .- Covering:
- Van Loon HJ et al., Am J Respir Crit Care Med 2005 Mar 1; 171:480-7.
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Pneumococcal Conjugate Vaccine Reduces Antibiotic Resistance
- October 8, 2004
- Neil M. Ampel, MD
Infections due to antibiotic-nonsusceptible pneumococci are on the rise worldwide. Reducing the incidence of invasive pneumococcal disease (IPD) is one way to tackle this problem. . . .- Covering:
- Talbot TR et al., Clin Infect Dis 2004 Sep 1; 39:641-8.
- Klugman KP., Clin Infect Dis 2004 Sep 1; 39:649-51.
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Antibiotic Resistance Reduces Efficacy of H. pylori Therapy
- October 27, 2003
- Neil M. Ampel, MD
Infection with Helicobacter pylori is associated with peptic ulcer disease, gastric cancer, and nonulcer dyspepsia. Antacid therapy plus antibiotics is recommended for treatment. However, antibiotic . . .- Covering:
- Wong WM et al., Clin Infect Dis 2003 Oct 1; 37:882-9.
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Antibiotic Resistance Increasing in Urinary Tract Pathogens
- April 1, 1999
- R Ellison
Because uncomplicated cystitis in women is caused by a limited number of microbial pathogens, with presumably predictable antibiotic susceptibility, urine cultures are often not performed . . .- Covering:
- Gupta K et al., JAMA 1999 Feb 24; 281:736-738.
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Fluoroquinolones: Treating TB Reduces Pneumococcal Susceptibility
- April 2, 2008
- Mary E. Wilson, MD
The use of fluoroquinolones to treat MDR-TB was associated with the emergence of pediatric invasive pneumococcal disease caused by levofloxacin-nonsusceptible organisms.- Covering:
- von Gottberg A et al., Lancet 2008 Mar 29; 371:1108.
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Gut E. coli Resistance Patterns and Antibiotic Therapy
- February 13, 2008
- Thomas Glück, MD
Resistant strains, present in low numbers before antibiotic therapy, increased significantly 2 to 7 days after treatment started.- Covering:
- Raum E et al., Clin Microbiol Infect 2008 Jan; 14:41.
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No Antibiotics for Uncomplicated Skin and Soft-Tissue Infections
- November 7, 2007
- Thomas Glück, MD
A randomized, placebo-controlled trial showed no benefit for antibiotic therapy after surgical incision and drainage of uncomplicated skin and soft-tissue abscesses.- Covering:
- Rajendran PM et al., Antimicrob Agents Chemother 2007 Nov; 51:4044.
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Antimicrobial Use and Resistance in Europe
- August 1, 2007
- Thomas Glück, MD
Antibiotic use varies greatly among the European countries and is closely correlated with antimicrobial resistance in Streptococcus pneumoniae.- Covering:
- Riedel S et al., Eur J Clin Microbiol Infect Dis 2007 Jul; 26:485-90.
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Antibiotic Resistance in Community-Associated MRSAFree!
- March 28, 2007
- Daniel J. Diekema, MD, MS
Clindamycin, tetracycline, and mupirocin resistance are emerging in community-associated MRSA.- Covering:
- Han LL et al., J Clin Microbiol 2007 Feb 7;:
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Appropriate Treatment of Bacteremic Nosocomial Pneumonia — Back to Surveillance Cultures?
- December 13, 2006
- Thomas Glück, MD
Tracheal surveillance cultures provided significant benefit in detecting the pathogens responsible for bacteremic nosocomial pneumonia.- Covering:
- Depuydt P et al., Intensive Care Med 2006 Nov; 32:1773-81.
You searched for: antibiotic resistance Items 1 to 20 of 94 results