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Search for HIV in Infectious Diseases
Physician-authored summaries on the latest research on HIV, editorials on HIV, and perspectives on HIV - drawn from the top medical journals.
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You searched for: HIV in Infectious Diseases
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Why Can't We Cure HIV Infection?
- September 21, 2011
- Rajesh T. Gandhi, MD
- Infectious Diseases
Cell-to-cell spread of HIV in vitro is relatively insensitive to antiretroviral drugs, but the clinical implications of this finding are not yet known.- Reviewing:
- Sigal A et al., Nature 2011 Sep 1; 477:95.
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HIV Transmission from a Living Organ Donor
- March 30, 2011
- Stephen G. Baum, MD
- Infectious Diseases
HIV was transmitted by transplantation of a kidney from a living donor who became infected after being tested.- Reviewing:
- Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Mar 18; 60:297.
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HIV and Stroke
- February 9, 2011
- Rajesh T. Gandhi, MD
- Infectious Diseases
The proportion of hospitalized stroke patients who are HIV-infected is increasing; multiple reasons are likely.- Reviewing:
- Ovbiagele B and Nath A., Neurology 2011 Feb 1; 76:444.
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Neurological Complications of HIV Disease
- December 15, 2010
- Richard T. Ellison III, MD
- Infectious Diseases
Mild neurological impairment remains common in HIV-infected patients.- Reviewing:
- Heaton RK et al., Neurology 2010 Dec 7; 75:2087.
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Predicting Treatment Success for Hepatitis C Among HIV-Infected Patients
- October 20, 2010
- Neil M. Ampel, MD
- Infectious Diseases
The rs12979860 CC genotype was associated with an increased likelihood of sustained viral response after pegylated interferon alfa-2/ribavirin treatment.- Reviewing:
- Pineda JA et al., Clin Infect Dis 2010 Oct 1; 51:788.
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2009 H1N1 Influenza in HIV-Positive Patients
- October 13, 2010
- Rajesh T. Gandhi, MD
- Infectious Diseases
Outcomes seem to be no worse among HIV-positive patients (at least those with well-controlled disease who were admitted to the hospital) than among other patients.- Reviewing:
- Riera M et al., AIDS 2010 Sep 4;:
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Excess Mortality in Untreated HIV-Infected Patients with High CD4-Cell Counts
- July 28, 2010
- Rajesh T. Gandhi, MD
- Infectious Diseases
In a large, multinational cohort study, the death rate among such patients varied by risk group but was higher than in the general population.- Reviewing:
- Lodwick RK et al. for the Study Group on Death Rates at High CD4 Count in Antiretroviral Naive Patients., Lancet 2010 Jul 16;: Bassett IV and Sax PE., Lancet 2010 Jul 16;:
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Hemophagocytic Syndrome in HIV-Infected Patients
- June 9, 2010
- Rajesh T. Gandhi, MD
- Infectious Diseases
Lymphomas and tuberculosis were the most common underlying causes of reactive hemophagocytic syndrome.- Reviewing:
- Fardet L et al., AIDS 2010 Jun 1; 24:1299.
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HIV/HSV-2 Coinfection: Disappointing Results for Acyclovir Suppression Free
- January 20, 2010
- Rajesh T. Gandhi, MD
- Infectious Diseases
HSV-2 suppression with acyclovir did not reduce the risk for HIV transmission.- Reviewing:
- Celum C et al., N Engl J Med 2010 Jan 20;:
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Kidney Disease and Cardiovascular Events in HIV-Infected Patients
- January 13, 2010
- Rajesh T. Gandhi, MD
- Infectious Diseases
Decreased renal function is associated with an increased risk for cardiovascular events in HIV-infected patients.- Reviewing:
- George E et al., AIDS 2009 Dec 17;:
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Undiagnosed HIV Infection: What We Don't Know Can Hurt Us
- December 16, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
The percentage of HIV infections in the U.S. that are undiagnosed is particularly high among blacks, high-risk heterosexual men, and young people.- Reviewing:
- Campsmith ML et al., J Acquir Immune Defic Syndr 2009 Oct 15;:
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HIV Controllers and Long-Term Nonprogressors
- November 25, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
HIV controllers and long-term nonprogressors represent overlapping but distinct groups.- Reviewing:
- Okulicz JF et al., J Infect Dis 2009 Dec 1; 200:1714. Hunt PW., J Infect Dis 2009 Dec 1; 200:1636.
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IL-2 and HIV: Two Definitive Studies Published
- October 14, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
Although interleukin-2 raises CD4-cell counts in HIV-infected patients, it does not improve clinical outcomes.- Reviewing:
- The INSIGHT–ESPRIT Study Group and SILCAAT Scientific Committee., N Engl J Med 2009 Oct 15; 361:1548.
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New Hope for HIV Vaccine Development
- September 16, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
Using a novel technique, researchers identified antibodies that neutralize a broad array of HIV strains.- Reviewing:
- Walker LM et al., Science 2009 Sep 3;:
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Women and HIV: More Work to Be Done
- August 5, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
The age-matched death rate remains much higher among HIV-infected women than among HIV-uninfected women, despite a decrease in AIDS-related deaths.- Reviewing:
- French AL et al., J Acquir Immune Defic Syndr 2009 Aug 1; 51:399.
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Cutaneous Non–AIDS-Defining Cancers in HIV-Infected Individuals
- July 1, 2009
- Larry M. Baddour, MD
- Infectious Diseases
Such cancers are not associated with immune status or receipt of ART.- Reviewing:
- Crum-Cianflone N et al., Arch Intern Med 2009 Jun 22; 169:1130.
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HIV, Inflammation, and Atherosclerosis
- May 13, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
HIV elite controllers are at higher risk for atherosclerosis than HIV-negative individuals, perhaps because of chronic inflammation.- Reviewing:
- Hsue PY et al., AIDS 2009 Apr 22;:
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Developing an HIV Vaccine: We Bait, the Virus Switches Free
- April 22, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
One study demonstrates a promising technique for identifying neutralizing antibodies against HIV; a second highlights the challenge of HIV evolution to avoid T-cell responses.- Reviewing:
- Scheid JF et al., Nature 2009 Apr 2; 458:636. Burton DR and Poignard P., Nature 2009 Apr 2; 458:584. Kawashima Y et al., Nature 2009 Apr 2; 458:641.
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Survival of HIV-Infected ICU Patients Continues to Improve
- February 11, 2009
- Thomas Glück, MD
- Infectious Diseases
Sixty-nine percent of HIV-infected patients admitted to an ICU from 2000 through 2004 were discharged alive.- Reviewing:
- Powell K et al., Chest 2009 Jan; 135:11.
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Rethinking Guidelines for HIV-Infected HCWs
- February 11, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
No cases of HIV infection were found in patients who were operated on by an HIV-infected cardiothoracic surgeon.- Reviewing:
- Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2009 Jan 9; 57:1413.
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