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Physician-authored summaries on the latest research on AIDS, editorials on AIDS, and perspectives on AIDS - drawn from the top medical journals.
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You searched for: AIDS in Infectious Diseases
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AIDS-Associated PCP in the U.S.
- August 5, 2009
- Thomas Glück, MD
- Infectious Diseases
Hospital discharge data indicate that hospitalizations for and mortality from AIDS-associated Pneumocystis jirovecii pneumonia have decreased significantly since 1986.- Reviewing:
- Kelley CF et al., Chest 2009 Jul; 136:190.
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AIDS-Related Cancers in Patients Who Interrupt HIV Therapy
- October 3, 2007
- Rajesh T. Gandhi, MD
- Infectious Diseases
The risk for AIDS-defining malignancies is greater among HIV-infected patients who interrupt ART than among those who receive continuous treatment.- Reviewing:
- Silverberg MJ et al., AIDS 2007 Sep; 21:1957.
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AIDS and Death Despite High CD4-Cell Counts
- August 29, 2007
- Rajesh T. Gandhi, MD
- Infectious Diseases
AIDS-related events and deaths occur even in HIV-infected patients with high CD4-cell counts; whether this means treatment should be started earlier is not certain.- Reviewing:
- The UK Collaborative HIV Cohort (CHIC) Study Steering Committee, AIDS 2007 Aug 20; 21:1717-21.
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Cancer and AIDS: A Mixed Report Card
- August 16, 2006
- Rajesh T. Gandhi, MD
- Infectious Diseases
Despite sizeable declines in Kaposi sarcoma and non-Hodgkin lymphoma, these and other cancers continue to occur at high rates in individuals with AIDS.- Reviewing:
- Engels EA et al., AIDS 2006 Aug 1; 20:1645-54.
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HIV/AIDS Update: Pediatric Treatment Guidelines
- March 19, 2008
- Robert S. Baltimore, MD
- Infectious Diseases
These guidelines, developed for the U.S., provide detailed information on ART for HIV-infected children.- Reviewing:
- Working Group on Antiretroviral Therapy and Medical Management of HIV-Infected Children., 2008 Feb 28;:
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Sustained Antiretroviral Therapy and Mortality Among the HIV-Infected Urban Poor
- February 28, 2005
- Neil M. Ampel, MD
- Infectious Diseases
Although mortality rates among persons infected with HIV have dropped dramatically in the U.S. since 1995, mortality remains disproportionately high among blacks, women, injection-drug users, . . .- Reviewing:
- Riley ED et al., J Acquir Immune Defic Syndr 2005 Feb 1; 38:191-5.
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When Did HIV Emerge?
- October 15, 2008
- Rajesh T. Gandhi, MD
- Infectious Diseases
Analysis of a newly discovered HIV sequence from 1960 suggests that the virus entered the human population around the beginning of the twentieth century.- Reviewing:
- Worobey M et al., Nature 2008 Oct 2; 455:661.
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Increased Estimates of HIV Incidence in the U.S.
- August 13, 2008
- Richard T. Ellison III, MD
- Infectious Diseases
About 56,000 people acquired HIV infection in 2006; 45% were blacks, and 53% were men who have sex with men.- Reviewing:
- Hall HI et al., JAMA 2008 Aug 6; 300:520.
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2009 H1N1 Influenza in HIV-Positive Patients
- October 13, 2010
- Rajesh T. Gandhi, MD
- Infectious Diseases
Outcomes seem to be no worse among HIV-positive patients (at least those with well-controlled disease who were admitted to the hospital) than among other patients.- Reviewing:
- Riera M et al., AIDS 2010 Sep 4;:
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For Cryptococcal Meningitis, Is More Fluconazole Better?
- December 17, 2008
- Neil M. Ampel, MD
- Infectious Diseases
Among HIV-infected patients in Uganda, cryptococcal infection was cleared more rapidly with 1200 mg daily than with 800 mg daily.- Reviewing:
- Longley N et al., Clin Infect Dis 2008 Dec 15; 47:1556.
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When to Initiate ART?
- February 13, 2008
- Stephen G. Baum, MD
- Infectious Diseases
This computer model predicts that 30-year-old patients and some 40-year-olds will benefit from initiating ART early in the course of HIV infection.- Reviewing:
- Braithwaite RS et al., Ann Intern Med 2008 Feb 5; 148:178.
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Cutaneous Non–AIDS-Defining Cancers in HIV-Infected Individuals
- July 1, 2009
- Larry M. Baddour, MD
- Infectious Diseases
Such cancers are not associated with immune status or receipt of ART.- Reviewing:
- Crum-Cianflone N et al., Arch Intern Med 2009 Jun 22; 169:1130.
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ART and Kaposi Sarcoma: Mostly Good News
- September 9, 2009
- Rajesh T. Gandhi, MD
- Infectious Diseases
Antiretroviral therapy alone is generally effective in controlling early-stage Kaposi sarcoma.- Reviewing:
- Bower M et al., AIDS 2009 Aug 24; 23:1701.
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Treatment of HIV Infection: Updated Guidelines from the IAS–USA Free
- August 27, 2008
- Rajesh T. Gandhi, MD
- Infectious Diseases
The panel recommends that HIV-infected patients with CD4 counts <350 cells/mm3 be treated and that therapy be considered in patients with higher CD4 counts.- Reviewing:
- Hammer SM et al., JAMA 2008 Aug 6; 300:555.
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Venous Thromboembolism in HIV-Infected Patients
- July 16, 2008
- Rajesh T. Gandhi, MD
- Infectious Diseases
Recent hospitalization is the strongest risk factor for VTE in HIV-infected patients.- Reviewing:
- Ahonkhai AA et al., J Acquir Immune Defic Syndr 2008 Jul 1; 48:310.
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HIV and the Kidney
- March 5, 2008
- Rajesh T. Gandhi, MD
- Infectious Diseases
Antiretroviral therapy improves renal function in HIV-infected patients with chronic kidney disease and low CD4-cell counts.- Reviewing:
- Kalayjian RC et al., AIDS 2008 Feb 19; 22:481.
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Cancers in HIV-Infected People and Transplant Recipients
- July 25, 2007
- Mary E. Wilson, MD
- Infectious Diseases
Risk for a wide range of cancers, especially infection-related cancers, is increased in these populations.- Reviewing:
- Grulich AE et al., Lancet 2007 Jul 7; 370:59-67. Clifford G and Franceschi S., Lancet 2007 Jul 7; 370:6-7.
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Multidrug-Resistant HIV: A Tale of Two Transmission Events
- April 11, 2007
- Daniel J. Diekema, MD, MS
- Infectious Diseases
More information about the multidrug-resistant HIV strain associated with rapid progression to AIDS in a New York City man- Reviewing:
- Blick G et al., J Infect Dis 2007 May 1; 195:1250-9. Hecht FM et al., J Infect Dis 2007 May 1; 195:1239-41.
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Nucleoside-Sparing Regimens: The Switch Is Not Yet On
- February 14, 2007
- Rajesh T. Gandhi, MD
- Infectious Diseases
In HIV-infected patients on successful therapy, switching to a nucleoside-sparing regimen led to higher treatment-failure rates than did switching to two nucleosides plus efavirenz.- Reviewing:
- Fischl MA et al., AIDS 2007 Jan 30; 21:325-33.
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Treating Lipodystrophy in HIV-Infected Patients
- December 20, 2006
- Rajesh T. Gandhi, MD
- Infectious Diseases
In HIV-infected patients with lipodystrophy, metformin and rosiglitazone improved insulin sensitivity but had limited effects on abnormal fat redistribution.- Reviewing:
- Mulligan K et al., AIDS 2007 Jan 2; 21:47-57.
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