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Infectious Diseases

Concise physician-authored perspectives on the most clinically relevant original research, guidelines, and new drug and vaccine approvals critical to the treatment, diagnosis, and prevention of infectious diseases.


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SUMMARY AND COMMENT

Assays for Invasive Fungal DiseaseFree

Two new antigen-based tests show promise and could prove useful for immunocompromised patients.

Recent Infectious Diseases Articles

SUMMARY AND COMMENT

L-AmB vs. D-AmB for Cryptococcal Meningitis in Solid-Organ Transplant Recipients

Ninety-day mortality was significantly better with lipid formulations of amphotericin B than with the deoxycholate formulation.

SUMMARY AND COMMENT

Bait and Switch — Vaccinia Infection from Animal Rabies Vaccine

Contact with liquid vaccinia-rabies glycoprotein recombinant virus vaccine, used to prevent rabies spread among animals, caused vaccinia infection in an immunocompromised woman.

SUMMARY AND COMMENT

Lipid-Lowering Therapy in HIV-Infected Patients

Gemfibrozil levels are reduced by lopinavir/ritonavir coadministration, which may explain the difficulty in lowering triglycerides in HIV-infected patients.

SUMMARY AND COMMENT

Background Events and Mass VaccinationFree

Knowledge about background rates of disease events is needed to assess events temporally related to vaccination.

SUMMARY AND COMMENT

Pneumococcal DNA Load in CAP

The Streptococcus pneumoniae DNA load in blood may have both diagnostic and therapeutic implications.

SUMMARY AND COMMENT

Acetaminophen After Vaccination Reduces Antibody ResponseFree

Prophylactic doses of acetaminophen given after vaccination reduce fever but blunt antibody response to multiple antigens.

DRUG WATCH

Peramivir for Treatment of 2009 H1N1 Influenza

Responding to a CDC request, the FDA authorized the emergency use of this investigational agent in critically ill patients.

SUMMARY AND COMMENT

Hepatitis E Outbreak Among Cruise Ship Passengers

Overall, 4% of passengers returning from a 3-month world cruise tested positive for recent HEV infection; one third of these individuals had symptomatic hepatitis.

SUMMARY AND COMMENT

Nontuberculous Mycobacterial Infections of the Cheek

Researchers describe a series of seven children with such infections. Recovery took many months, and clarithromycin did not seem to hasten resolution.

SUMMARY AND COMMENT

Antibiotic Prophylaxis for Children with UTIsFree

Prophylaxis was associated with a modest but significant reduction in recurrent UTI.

Browse our complete Infectious Diseases archive >>

Editor's Picks from across Journal Watch

SUMMARY AND COMMENT

Can HPV Vaccination Combat Genital Warts?

Yes — and the benefit extends beyond vaccinated women to their male sexual partners.

SUMMARY AND COMMENT

Second-Regimen Failure and Mortality Risk

Although second-regimen failure and associated mortality declined significantly between 1996/1997 and 2005, the mortality risk remained high.

SUMMARY AND COMMENT

Immune Activation Persists Despite Effective ARTFree

In a cohort of HIV-positive patients, markers of immune activation remained elevated despite 6 years of effective antiretroviral therapy. Immune activation was associated with lower CD4-cell counts.

SUMMARY AND COMMENT

Viramidine vs. Ribavirin for Hepatitis C Infection

The ribavirin prodrug viramidine failed to demonstrate noninferiority to ribavirin in achieving sustained virologic response rates.

More Editor's Picks >>

Journal Watch Infectious Diseases summarizes important medical journal articles about a wide variety of infectious disease subjects including antibiotic resistance, hepatitis, HIV, influenza, malaria, pneumonia, sepsis, sexually transmitted diseases, and tuberculosis.

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Infectious Diseases Editor-in-Chief

Larry M. Baddour, MD
Larry M. Baddour, MD
Professor of Medicine, Division of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota

More about Journal Watch Infectious Diseases and its board >>

Journals Watched: Infectious Diseases >>

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